This issue has been discussed elsewhere in "The D800/D800E are reality!" regarding the D800. I only have a Intel dual core processor and 4 Gb memory and as I've mentioned in my thread, see below, by scrupulous housekeeping of my 6 year old PC I have no problems loading D700 files with Photoshop CS5, Lightroom 3 and sometimes Nikon Capture NX2 all open. Your quad core processor and 8Gb memory should eat the task of D800 files. It's not all about hard disk clutter, but it certainly does have a significant impact on process efficiency. I also have a i7 with the same programs loaded and 4Gb Ram and likewise I work in the same fashion, but not with to marked difference.