Definitely. As a developer I look at the question a little differently. It's more about how fast the computer will be to accomplish the task. I doubt any modern computer (~3-4 years) would have an issue. It'll just be slower. I have a dual core first gen i7 processor with 8 gb memory. Doing a major filter operation with Nik on my D700 files generally take 15-30 seconds. I'd expect that to turn into a 60-90 second operation. Annoying but definitely workable. Storage space would then become more of an issue. I'd have to become more choosy in what I keep.