I usually leave the settings at Jason's recommendations
High Pass: Radius 1, Opacity Overlay blending mode at 85%.
USM: Intensity 100%, Radius 1, Threshold 5.
This works fine for landscapes and other nature. For portraits I would probably soften this a bit by backing off on the USM intensity.
From what I've read you would be better off setting the sharpening to zero in the develop section. This sharpening is just a USM step where you are changing the intensity without being able to control the radius or threshold. I leave the picture control settings normal in the camera to be able to better judge the image on the LCD. In CNX2 Camera Settings I change the Picture Control from "Unchanged" to the one I want for the image. Usually I select the same picture control as I used in the camera. Doing this allows me to change the in camera sharpening under the "Advanced" arrow point. I move the slider to zero. Now I have full control of the image sharpening in my edit steps.
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