To add to what Gary said for the NEF file you can use compressed or uncompressed in 12 or 14 bit. If you are shooting and need to save more room on your card step down to 12 bit compressed and it will save you some room on your card. An uncompressed 14bit RAW NEF files is about 74MB and a 12bit is 57MB. A compressed 14bit RAW NEF is around 35MB and a 12 bit is around 29MB. And Lossless compressed is somewhere in the middle. This is where you can save yourself some space when you need it. I think the chart is on page 436 in the manual.