Whether I use Vivid or some of the other picture controls (I have a Canon Vivid and Canon Neutral as well in my camera) depends on what my subjects are. NEF's aren't affected by the picture controls set in the camera unless you use ViewNX or CaptureNX. For jpeg's the story is different of course. For subtle transitions in the sky for instance I tend to stick with no or very moderate boost of contrast/clarity/sharpening in ACR as this has a nasty habit of creating banding. Despite the D800's DR I often use selective contrast enhancements in order to avoid the banding issues.