I intend to study my settings someday, but Larry's comments about generalizing the two might offer a methodology to begin to differentiate or optimize in a better way.
Meanwhile what I suggest is keep ALL of your important variables also in MyMenu so that you can keep track of where they are at currently. I.e. things that you change from time to time and that you need to keep an eye on. For me that includes things like Picture Control, ADL, NR, Focus tracking with Lock On, WB, Movie settings, and especially Auto-ISO settings which is always my top setting and instantly recalled by pressing the function button.