I use center-weighted metering with aperture priority or manual exposure most of the time, and spot metering when the occasion demands. I was somewhat unhappy with the fact that at times matrix metering recommend very different exposure when I changed the composition only slightly. I guess I have grown so used to center-weighted metering that I am more confident that I can better predict the resulting outcome. I find that I make fewer exposure adjustments with center-weighted metering than with matrix.
I do use matrix metering for certain situations - such as when I want to use the camera in the full-auto Program mode while chasing my grandchildren around in the park where lighting can vary significantly (and the kids move pretty fast). Under these circumstances I don't want to take the time to think about each shot. But I still capture in raw + JPEG so that if I happen to get a really good image but I don't care for the exposure chosen by the camera I have the raw file to give me a little better chance of rescuing the image.