The real advantage of PS is the way you can use layers and selectively apply sharpening and noise reduction as needed. You might even add Texture to the list. I don't think any global setting will really optimize high ISO images using any software program. By definition, if you are sharpening you are accentuating noise, and if you use noise reduction the image gets softer. For high ISO images, you have to deal with specific parts of your image.
If you get good results sharpening your subject in LR or Photoshop, by all means use those tools as a layer. But the noise reduction and noise management is probably going to be needed for the rest of your image - the background and other areas that may have noise but don't need the same level of sharpness. So you need a "low noise" or "Noise managed" layer for your image. You would combine the two layers in PS using the sharp subject and low noise background.
If you get good results sharpening your subject in LR or Photoshop, by all means use those tools as a layer. But the noise reduction and noise management is probably going to be needed for the rest of your image - the background and other areas that may have noise but don't need the same level of sharpness. So you need a "low noise" or "Noise managed" layer for your image. You would combine the two layers in PS using the sharp subject and low noise background.