After Media Pro came out, I abandoned Lightroom altogether, because the combination of Media Pro for catalogues and Capture One for Raw was better for my use. However, a big frustration was losing the ability to apply gradient masks which Lightroom supported but Capture One didn't. You could use the paintbrush tool to paint in a kind of gradient, and that's what I often did, but it was tedious when there was consistent light fall off. Phase One has risen to the challenge, and you are now able to have as many layers as you want with different kinds of masks, including gradients. These only control exposure, colour, sharpening, moire and clarity, so you can't selectively apply a different colour temperature (which would have been very useful for multi-temperature images) or HDR.
In daily use, gradient masks are the biggest benefit for me, meaning that there is no longer a requirement to go into Photoshop at all unless I'm doing my own graphic design work.