You don't want to crop excessively, but you can crop modestly and have enough pixels to print larger. If you cropped an image down to say 3600 x 2400 pixels, you could print at 300 ppi and get an 12 x 8 inch print. Or at 150 ppi, you would get a 24 x 16 inch print. A lot depends upon the quality of the image, i.e. how sharp it is, etc., and from what distance the print will be viewed. If you want huge prints, you will need to buy a D800.