Very good thread. I am retired now but spent many years working on DR & BR solutions for Fortune 500 businesses.
Reading through all the posts the bulk of the discussion is focused on a technology failure. The other major threat is a physical disaster such as fire and there were a couple of references to offsite storage.
If I'm on an extended trip my personal workflow is I transfer the images to my laptop and burn a DVD. This way if I need to, I can format my CF cards and still have two physical copies. When I get home I transfer the DVDs to my desktop that also has a 750GB backup drive and then take the DVDs to my safe deposit box at the bank. I should burn two DVDs but I compensate for it by burning another DVD of the master files after I have worked on them in CS3.
If I'm just shooting day trips I transfer the images to my desktop and leave the images on my CF cards. I now have 3 physical copies: my CF cards, primary disk on my desktop and a copy on my backup drive. When my CF card is full I know I've hit 4 GB and burn a DVD and off to the bank. My images are vulnerable to a physical disaster between DVD burns.
50 gb disks in a Bluray format will have a really positive impact on my workflow. I will still have to burn 4gb DVDs just to make sure I'm safe between 50gb burns but offsite storage and management will be even simpler.
Anyway, great topic that needs to be discussed on a regular basis.....Mark