#2. "RE: Suggested Settings for photographing Artwork" In response to Reply # 0
Actually in my opinion an indoor lighting setup is not all that difficult and would be more consistent and controllable. Two umbrellas with Speedlights placed at 45 degree angles equidistant from the artwork are all that is needed. Also you need to make sure that the artwork and sensor are properly aligned to prevent perspective distortion.
But more than camera settings, your main concern well be with color management. Producing accurate reproductions will require a thorough understanding of color management and a meticulous workflow. The color space of your camera is different than the color space of your monitor which is different from the color space of printers. Knowing the subtle differences in viewing mediums and how to soft-proof will be the only way to achieve close accurate reproductions.
As for camera settings I would imagine shooting NEF’s and using the Adobe RGB color space would be the way I would recommend you do it (actually I prefer to use ProPhoto RGB as my color space). I would then develop the images to produce an accurate rendering for the medium to which it will be printed and the conditions it will be viewed under. But again, good color management skills will be paramount in the ability of producing consistent results and accurate reproductions.